Not medical advice. A study aid built automatically from public databases — sources and AI processing can be wrong. Never use for diagnosis or treatment.Study aid only — it can be wrong. About PathoRx
Catalogue
R-HSA-177929

R-HSA-177929

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Apply a drug from the rail to trace the effect this diagram implies for it — inferred by multiplying signs along the drawn relations, not measured.
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Drugs acting here
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CHEMBL1173655on this pathway
  1. 1
    Binds …
    One protein can be drawn in several forms (in complexes, phosphorylated). Each form is ringed; the tag sits on one and counts them.
  2. 2
    Next step, from papers … · cited
  3. 3
    Further along, predicted off (turn on “Drug effects”) · inferred
How the three steps differ

1 is ChEMBL’s record of what the drug binds. 2 is what published papers say those targets do next, one step, each with its citation in the panel below. 3 is a prediction: the diagram’s arrows multiplied out from the target — neither measured nor cited.

Recorded downstreamcited · not inferred

What published sources say, each with its citation.

How this differs from “Drug effects”

Every line here is a statement a database recorded, copied as written, with the paper it came from. Nothing is chained together or predicted.

“What X does” lists statements about the drug’s target, one step. They are never combined with the drug’s own action into a conclusion about a gene further along — that would be an inference, and inference lives only in the separate “Drug effects” layer.

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