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1 is ChEMBL’s record of what the drug binds. 2 is what published papers say those targets do next, one step, each with its citation in the panel below. 3 is a prediction: the diagram’s arrows multiplied out from the target — neither measured nor cited.
What published sources say, each with its citation.
Every line here is a statement a database recorded, copied as written, with the paper it came from. Nothing is chained together or predicted.
“What X does” lists statements about the drug’s target, one step. They are never combined with the drug’s own action into a conclusion about a gene further along — that would be an inference, and inference lives only in the separate “Drug effects” layer.